UAIPD 13-0018: Iron Oxide Nanoparticles with Surface Capping Molecules
Iron Oxide Nanoparticles with Surface Capping Molecules
Iron oxide nanoparticles (NP) with different surface capping molecules for use as MALDI matrices. Attachment of capping molecules to a NP surface reduces matrix molecule self-clustering and fragmentation (a common problem with organic matrices), which in turn minimizes the intensity of low mass background ions that can complicate the mass spectra. These NP matrices are versatile and selective because varying the surface capping molecule yields different chemical preferences and targets different analytes in a sample.